Paul F. Cancalon, D. King
The majority of the health benefits of fruits are believed to be due to a series of phytochemicals; among them, the polyphenols have been the most studied. Citrus fruit and juices are rich in flavonoids (primarily flavonones), with the two more prominent being hesperidin in oranges and naringin in grapefruit. Citrus products are also rich in other potentially beneficial compounds such as carotenoids, limonoids and vitamin C. Most beneficial effects of citrus phytochemicals seem to be related to specific steps of the chronic inflammation process. Persistent inflammation is considered to be at the root of most chronic diseases, including cardiovascular diseases, metabolic syndrome, osteoporosis, dementia and some forms of cancer. The strongest clinical evidence to date has provided insight into both the physiological responses and mechanisms of response to citrus juice consumption in potentially reducing risk of development of cardiovascular disease, and to the role of citrus consumption on benefits to cognitive activities and function. However, it should be kept in mind that fruits and juices are not drugs, and that the beneficial effects will be mild and without the more dramatic effects expected with drug therapies.
Paul F. Cancalon, and King, D. (2015). HEALTH BENEFITS OF POLYPHENOL-RICH ORANGE AND GRAPEFRUIT JUICES. Acta Hortic. 1065, 727-734
DOI: 10.17660/ActaHortic.2015.1065.91
citrus, flavonones, inflammation, chronic diseases, hesperidin, naringin, polymethoxylated flavones, carotenoids

Acta Horticulturae