Metabolite production from hairy root biomass in Salvia species

Numerous plant species have been used to create hairy root cultures, which are caused by an infection with the bacterium Agrobacterium rhizogenes. Hairy root cultures typically maintain a steady degree of biosynthetic ability while accumulating phytochemicals at quantities comparable to those of entire plants. Hairy roots can be cultivated in industrial-scale bioreactors when they are adapted for liquid cultures, offering a practical, abundant, and sustainable supply of phytochemicals. Due to these properties, hairy root culture emerged as an appealing tool in the generation of metabolites. This review provides a concise description of the key developments in the use of hairy root cultures for Salvia species. Salvia species’ transformed root cultures are rich in polyphenols, diterpenoids, and triterpenoids. These chemicals exhibit a range of biological properties, including the ability to activate the apoptotic process as well as antibacterial, cytotoxic, anticancer, and anti-inflammatory effects.