GASTROINTESTINAL MOTILITY MODULATION WITH IBEROGAST
The fresh plant extract of Iberis amara (1) increased the basal resting tone and contraction of atonic and slightly contracted gut segments. The herbal extracts (2) inhibited the contractile action of acetylcholine on the guinea pig ileum. The phytopharmacon Iberogast displayed a dual action, increased tone and contraction of atonic and hypotonic ileum and relaxed the strongly contracted.
The presented pharmacological evidences of dual action explain, at least in part the therapeutic usefulness of Iberogast in relieving both spastic and hypotonic dysmotility symptoms of dyspeptic diseases and irritable bowel syndromes alike.