CASSAVA INTAKE AND RISK OF DIABETES IN HUMANS
There are human and animal data for and against the hypothesis that cyanide from cassava may be an etiological factor in diabetes. Recent work from my laboratory and elsewhere, using human and animal models, indicates that the likelihood appears remote, that cyanide-induced pancreatic islet damage and diabetes constitute a distinct clinico-pathological entity, as suggested by the WHO Expert Committee on Diabetes. Our studies in rats suggest that cassava may have a diabetogenic potential independent of its cyanogenic potential. Such potential may be mediated by malnutrition.